Journal of Pure and Applied MicrobiologyVol. 6 No. 1

Effect of Antibiotics on Growth and L-glutamic Acid Fermentation by the Mutant Micrococcus glutamicus AB100

S. Ganguly* and A.K. Banik

Department of Chemical Engineering Biochemical Engineering Division, Biotechnology Laboratory, University of Calcutta, 92, A. P. C. Road, Kolkata - 700 009, India.

Received on 10 April 2011 and accepted on 25 May 2011



An experimental study was conducted to investigate the effects of varying concentrations (10-30 µg/ml) of different antibiotics namely penicillin G, erythromycin, chrompheniol, streptomycin, tetracycline and gentamicin added to the fermentation broth at different time intervals (0-48h) on growth and l-glutamic acid production by the biotin-auxotrophic mutant Micrococcus glutamicus AB100. All these antibiotics showed determental effect on both growth & l-glutamic acid production.

Keywords : Experimental, Antibiotics, Growth, L-glutamic acid.