Journal of Pure and Applied MicrobiologyVol. 2 No. 1

Effect of Aqueous Cranberry (Vaccinium arctostaphylos L.) Extract Accompanied with Antibiotics on Urinary Tract Infections caused by Escherichia coli in vitro

Arezou Taherpour1, Parisa Noorabadi1, Farzad Abedii1 and Avat (Arman) Taherpour2*

1Medicinal Microbiology Department, Medicinal University of Kurdistan, Pasdaran Ave., Post Code: 66177-13446, Sanandaj, Kurdistan Province, Iran. 2Faculty of Science, Islamic Azad University, Sanandaj Branch, P.O. Box 618, Sanandaj, Kurdistan Province, Iran.

Received on 14 January 2008 and accepted on 12 March 2008



The chemical compositions of the different species of Cranberry were studied widely. In the most species of Cranberry some chemical compounds such as Flavonoids, sugar, protein, total fat and some important fatty acids were identified. Urinary tract infections (UTI) are common in women and children and they cause some permanent side effects on kidneys. Since many years, people for treatment of UTI, utilize this herb with or without appropriate antibiotics. In this study, the synergistic and/or antagonistic effect of aqueous Cranberry (Vaccinium arctostaphylos L.) extract accompanied with antibiotics (Ciprofloxacin, Amikacin, Ampicillin and Nitrofurantoin) was carried out on UTIs caused by Escherichia coli in vitro. The results show that because of suppression of the appropriate medicinal effect of antibiotics by Vaccinium arctostaphylos it is better not to use this medicinal herb for treating UTIs with the antibiotics.

Keywords : accinium arctostaphylos L., Urinary tract infections, Antibiotics, Escherichia coli.