Journal of Pure and Applied MicrobiologyVol. 2 No. 1

Bacteriology and Sensitivity profile Bacterial agents responsible for Neonatal Septicaemia in a tertiary hospital of Kaduna metropolis

E.E. Ella*, A.A. Ahmad¹, W.N. Ogala², V.J. Umoh¹ and R. Aliyu-Zubair³

*Centre for Biotechnology Research and Training, A. B. U. Zaria, Nageria. ¹Department of Microbiology, Ahmadu Bello University Zaria, Nageria. ²Department of Paediatrics, Ahmadu Bello University Teaching Hospital Shika, Zaria, Nageria. ³Barrau Dikko Specialist Hospital Kaduna, Nageria.

Received on 10 February 2008 and accepted on 18 March 2008



A total of 50 samples and patients analyzed and out of these, 13 had evidence of bacterial growth, accounting for 26% Gram positive bacteria were isolated from 5 patients representing 10% of the total samples (n = 50) and 38.46% of the isolates (n = 13). Group B-Streptococcus was isolated from one patient, (7.69%), Staphylococcus aureus was also isolated from one patient (7.69%) while the remaining three gram positive isolates were coagulase negative Staphylococcus sp. (23.08%) while the remaining 8 isolates were gram negative organisms representing a prevalence of 16% and 61.54% of the total bacterial isolates. Enterobacter sp had the highest incidence accounting for 23% Klebsiella sp and Escherichia coli were 15.38%, Citrobacter flexneri 7.69%. The incidence of septicaemia was higher in males than in females with the ratio being 3:1 80% was sensitive to Cloxacillin, 60% of the gram positive bacteria were sensitive to chloramphenicol, augmentin and amoxicillin while 40% were sensitive to gentamicin and cotrimazole. All the isolates were resistant to tetracycline and only one isolate (20%) was sensitive to erythromycin. On the other hand there was a remarked resistance to the antibiotics among the gram negative bacteria with 100% to ampicillin, cotrimazole, nalizidic acid and colistin. The sensitivity to gentamicin, nitrofurantoin, streptomycin and tetracycline was only 12.5%.

Keywords : Neonatal Septicaemia, Bacterial, strains, Mortality and Morbidity.