Journal of Pure and Applied MicrobiologyVol. 9 No. 4

Optimal Conditions for Antimicrobial activity Production from two microalgae Chlorella marina and Navicula f. delicatula.

R. Elkomy*1, I.B.M. Ibraheem2, M. Shreadah1 and R. Mohammed3

1Biotechnology Laboratory-National Institute of Oceanography and Fisheries-Alexandria, Egypt. 2Botany and microbiology Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt. 3Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Egypt.

Received on 09 October 2015 and accepted on 03 November 2015

 

ABSTRACT

In the present investigation two marine microalgae (Chlorella marina and Navicula f. delicatula) had been chosen for the antibacterial and antifungal metabolites studies. The effects of pH, temperature and light intensity were tested for the production of antimicrobial activity. The antibacterial and antifungal effects of different solvent extracts (chloroform, acetone, ethanol, methanol and water) of two microalgae were tested by agar well diffusion method for their antibacterial and antifungal agent (Staphylococcus aureus, MicrococusLuteus, Serratiamarcescens, Pseudomonas aeruginosa, and Escherichia coli) and unicellular fungus (Candida albicans). Data showed that the pH, temperature and light intensity of the medium is very important for growth of microorganisms.

Keywords : Optimization, Antimicrobial activity, Microalgae, Marine.