Journal of Pure and Applied MicrobiologyVol. 8 No. Special Edition Nov. 2014

Evaluation of the Antioxidant Potential of Bioactive Compounds in Methanolic Extracts of Aerial Parts of Fagonia glutonosa

Mohamed M. Ibrahim1,2*, Ibrahim A. Alaraidh1 and G.A. El-Gaaly1

1Department of Botany and Microbiology, King Saud University, Science College, Riyadh 11451-P.O. Box 2455 2Department of Botany and Microbiology, Faculty of Science, Alexandria University, 21511, Alexandria, Egypt.

Received on 18 September 2014 and accepted on 28 October 2014



Fagonia glutonosa (L.) (Zygophyllaceae) is a medicinal plant traditionally used as an mainly as a popular remedy for the treatment of various skin lesions and for the treatment of various other digestive diseases. Preliminary phytochemical screening of the plant showed the presence of large amounts of phenolics and flavonoids, anthraquinones, terpenes, saponins, alkaloids, coumarins and tannins. Subsequent quantification showed the presence of 0.74% (m/m) phenolics (calculated as gallic acid) and 0.13% (m/m) flavonoids calculated as catechin equivalents per 100 g of fresh mass. The presence of phenolic compounds prompted us to evaluate its antioxidant activity. In the present study, methanolic extract of aerial parts of Fagonia glutonosa was screened to evaluate its free - radical scavenging effect. The highest antioxidant and free radical scavenging ability of the extract was observed at a concentration of 2500 µg mL–1.

Keywords : Fagonia glutonosa, medicinal plants, skin lesions.