ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Abdulilah Saleh Ismaeil and Fraidoon A. Saleh
Biology Department, Science College, Salahaddin University, Erbil, Kurdistan, Iraq.
J. Pure Appl. Microbiol., 2019, 13 (4): 2397-2404 | Article Number: 5824
https://doi.org/10.22207/JPAM.13.4.56 | © The Author(s). 2019
Received: 02/09/2019 | Accepted: 06/12/2019 | Published: 26/12/2019
Abstract

Different solvents were used for sumac extractions to find different active compounds in each fraction, and these fractions were tested on Staphylococcus aureus (which isolated from soft white cheese), the (MIC) minimum inhibitory concentration of each fraction were measured then sub-inhibitory concentration (SIC) was used. We found that all fractions can inhibit quorum sensing in Staphylococcus aureus in a different ratio. By using Real-time PCR found that the different sumac fractions can inhibit the expression of tested genes (Sea, Seb, AgrA, RNAIII, and Hla). Furthermore, most sumac extracted fractions have the ability to decreasing biofilm and growth curve in Staphylococcus aureus significantly, while other fractions decreased them non-significantly.

Keywords

Staphylococcus aureus, sumac extract, quorum sensing inhibitor, Biofilm, Growth curve.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.