ISSN: 0973-7510
E-ISSN: 2581-690X
In the recent years Nanotechnology has attracted the great attention to the researchers and pharmaceutical companies due to its immense application in the field of science and technology for the purpose of developing new nanomaterial’s . In our present study, nanosilver was bio-synthesized by extracellular method from Penicillium spinulosum (MTCC-4952). The development of dark brown color in the l flask by addition of AgNO3 indicates the formation of silver nanoparticles (AgNPs). These nanoparticles were confirmed by UV-Vis spectrophotometer which showed absorption peak at 416nm, Fourier transform infrared (FTIR), Field emission scanning electron microscopy (FESEM) and Atomic force microscopy (AFM). Size of the Nanoparticles was around 18nm by FESEM analysis. Silver nanoparticles showed good antibacterial activity against the selected bacterial pathogens but in combined activity with Amoxicillin and Ofloxacin enhanced the antibacterial property of the antibiotics studied.
Silver nanoparticles, Penicillium spinulosum (MTCC4952), FESEM, FTIR, AFM,UV-VIS Spectrophotometer
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