ISSN: 0973-7510

E-ISSN: 2581-690X

S. Vijaya Saradhi1 , G. Devala Rao2, P. Srinivasu2 and B.S.S.Venkatesh2
1Department of Biotechnology, Koneru Lakshmaiah College of Engineering, Vaddeswaram – 522 502, India.
2K.V.S.R. Siddhartha College of Pharmaceutical Sciences, Vijayawada – 520 010, India.
3P.B. Siddhartha College of Arts and Science, Vijayawada – 520 010, India.
J Pure Appl Microbiol. 2007;1(2):313-315
© The Author(s). 2007
Received: 20/09/2007 | Accepted: 02/10/2007 | Published: 30/10/2007
Abstract

A simple, sensitive and reproducible spectrophotmetric method is developed for the determination of Atorvastatin calcium in bulk and dosage forms. This method is based on the formation of colour species on binding of Atorvastatin calcium with potassium ferro cyanide and ferric chloride to produce pale green coloured solution (l max  at 425 nm). Results of analysis were validated statistically and by recovery studies. This method is successfully employed for the determination of Atorvastatin calcium in various pharmaceutical preparations.

Keywords

Atorvastatin calcium, Visible Spectrophotometric determination, Beer’s Law

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© The Author(s) 2007. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.