ISSN: 0973-7510

E-ISSN: 2581-690X

Mustafa Kemal Celen1, Kamuran Turker2, Nefise Oztoprak3, Alper Sener4, Nazan Tuna5, Nevin Ince6, Ilknur Erdem7, Nese Saltoglu8, Davut Ozdemir9, Tuba Dal 10, Mustafa Karahocagil11, Fatma Sirmatel12, Fusun Zeynep Akcam13, Fatma Eksi Polat2, Mehmet Cabalak14,Suzan Sacar4, Selma Tosun15 and Fehmi Tabak8
1Dicle University Hospital, Department of Infectious Diseases. Diyarbakir.
2Bagcilar Training and Research Hospital, Department of Infectious Diseases, Istanbul, Turkey.
3Antalya Education and Research Hospital, Department of Infectious Diseases, Antalya, Turkey.
4Canakkale University, Department of Infectious Diseases. Canakkale.
5Sakarya University Hospital, Department of Infectious Diseases. Sakarya.
6Nevsehir State Hospital, Clinic of Infectious Diseases, Nevsehir.
7Namik Kemal University, Department of Infectious Diseases, Tekirdag.
8Cerrahpasa University, Department of Infectious Diseases, Istanbul, Turkey.
9Duzce University, Department of Infectious Diseases, Duzce.
10Dicle University Hospital, Clinical Microbiology, Diyarbakir.
11Van 100th Year University, Department of Infectious Diseases. Van.
12Abant Izzet Baysal University, Department of Infectious Diseases. Bolu.
13Isparta University, Department of Infectious Diseases. Isparta.
14Bingol State Hospital, Clinic of Infectious Diseases, Bingol.
15Manisa State Hospital, Clinic of Infectious Diseases, Manisa.
J Pure Appl Microbiol. 2014;8(4):3063-3068
© The Author(s). 2014
Received: 19/07/2013 | Accepted: 24/08/2013 | Published: 31/08/2014
Abstract

Chronic hepatitis B is a major public health problem in our country. Hepatitis A vaccination in HBV carriers who did not encounter with Hepatitis A virus is also significant. We aimed to evaluate the rate of exposure to HAV in HBsAg-positive persons, and the distribution of seronegative individuals according to age groups. Medical records of 4793 patients from 14 centers who were positive for hepatitis B surface antigen (HBsAg). A total 3514 cases (73.3%) were male and 1279 (26.7) were female. The HBsAg positive patients who were previously tested for HAV IgG at the time of firstly admitted to a center. HBsAg positive patients who were previously not tested for HAV IgG were tested and these patients were confirmed serologically for HAV. The distribution of cases according to age were determined. In this study, 4793 HBsAg-positive patients were evaluated. The ratio of testing of anti-HAV IgG was very low during the first visit (54.2%). Seronegativity was highest in the age group under 19 years of age (26.2%) followed by 20-25 age group (15.5%) and 26-29 age group (12.5%). Testing of HAV serology should not be ignored in especially HBsAg-positive young adults and seronegative young adults should be vaccinated.

Keywords

Hepatitis A, HBsAg, anti-HAV IgG

Article Metrics

Article View: 729

Share This Article

© The Author(s) 2014. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.