ISSN: 0973-7510

E-ISSN: 2581-690X

Mini Review | Open Access
Hafiz M. N. Iqbal1 , Kenya D. Romero-Castillo1, Muhammad Bilal2and Roberto Parra-Saldivar1
1Tecnologico de Monterrey, School of Engineering and Sciences, Campus Monterrey, Ave. Eugenio Garza Sada 2501, Monterrey, N.L., CP 64849, Mexico.
2School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huaian 223003, China.
J. Pure Appl. Microbiol., 2020, 14 (1): 13-16 | Article Number: 6146 | © The Author(s). 2020
Received: 29/02/2020 | Accepted: 08/03/2020 | Published: 09/03/2020

Recently, a new viral-based infection has emerged as a respiratory disease caused by a novel (new) coronavirus that was first detected in Wuhan City, China. With any or many reasons, this newly emerged novel-Coronavirus (2019-nCoV) has now been recognized in more than 70 locations around the globe. The disease caused by 2019-nCoV has been named as “coronavirus disease 2019 – COVID-19”. Due to the rising number of confirmed 2019-nCoV infected cases and widespread detection, the World Health Organization (WHO) has announced 2019-nCoV as a threatening health concern, and urgent robust actions are of supreme interest to tackle this global health emergency. Owing to this new emergence, we know relatively little about 2019-nCoV, which is a highly pathogenic human pathogen. To completely overcome this life-threatening 2019-nCoV pathogen, further in-depth studies are needed to gain insight and complete understanding about its fast mode spread, replication, and pathogenesis. Since the first appearance and detection of 2019-nCoV and COVID-19, respectively, the current literature lacks the global perspective and replication cycle of 2019-nCoV. Thus, herein, an effort has been made to cover this literature gap. A proper understanding of the 2019-nCoV replication will further insight and strengthen the infection control measures, transmission prevention, and vaccine development, effectively.


2019-nCoV, COVID-19, Emergence, Infection, Respiratory disease, Replication.

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