Salmonella enterica subspecies enterica serovar Enteritidis (SE) and Salmonella enterica subspecies enterica serovar Typhimurium (ST) are the zoonotic Salmonella that colonizes in the intestine of poultry asymptomatically and are transmitted to human by consumption of contaminated foods like meat, eggs and egg products. The PPIases are enzymes that accelerate folding of proline-containing proteins by catalyzing the cis-trans isomerisation, which plays important roles in a variety of stress responses in bacterium. In this study, the Peptidyl prolyl cis–trans isomerases C (ppiC) gene from ST was cloned, sequenced, analyzed and submitted to gene bank (accession number KR054755). The retrieved sequence data analysis, suggested that gene belongs to the parvulin family of peptidyl-prolyl cis/trans isomerases (PPIases, EC 22.214.171.124) of ST. Entertainingly, the ppiC sequence shows about 100% -99% with other Salmonella serovars. The conclusion of this study effectively indicate that ppiC gene of Salmonella is highly conserved in most of the pathogenic Salmonella spp. as analogous to patterns of other serovars.
Salmonella, Parvulin, PPIases C and ppiC.
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