ISSN: 0973-7510

E-ISSN: 2581-690X

Manoj Kumawat1, Sushma Ahlawat1 , Neeraj Ahlawat2, Pavan Kumar Pesingi3, Irungbam Karuna3, Prasanta Kumar Mishra3 and Ankita Gupta4
1Department of Biochemistry & Biochemical Engineering, JSBB, SHIATS, Allahabad, India.
2Departments of Animal Nutrition, SSAHD, SHIATS, Allahabad, India.
3Divisions of Biochemistry, Veterinary Public Health, IVRI, Izatnagar, India.
4Divisions of Biotechnology APS Vishwavidyalaya Rewa M.P. India.
J. Pure Appl. Microbiol., 2016, 10 (1): 463-469
© The Author(s). 2016
Received: 17/11/2015 | Accepted: 23/01/2016 | Published: 31/03/2016
Abstract

Salmonella enterica subspecies enterica serovar Enteritidis (SE) and Salmonella enterica subspecies enterica serovar Typhimurium (ST) are the zoonotic Salmonella that colonizes in the intestine of poultry asymptomatically and are transmitted to human by consumption of contaminated foods like meat, eggs and egg products. The PPIases are enzymes that accelerate folding of proline-containing proteins by catalyzing the cis-trans isomerisation, which plays important roles in a variety of stress responses in bacterium. In this study, the Peptidyl prolyl cis–trans isomerases C (ppiC) gene from ST was cloned, sequenced, analyzed and submitted to gene bank (accession number KR054755). The retrieved sequence data analysis, suggested that gene belongs to the parvulin family of peptidyl-prolyl cis/trans isomerases (PPIases, EC 5.2.1.8) of ST. Entertainingly, the ppiC sequence shows about 100% -99% with other Salmonella serovars. The conclusion of this study effectively indicate that ppiC gene of Salmonella is highly conserved in most of the pathogenic Salmonella spp. as analogous to patterns of other serovars.

Keywords

Salmonella, Parvulin, PPIases C and ppiC.

Article Metrics

Article View: 653

Share This Article

Journal Tools

© The Author(s) 2016. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.