ISSN: 0973-7510

E-ISSN: 2581-690X

S.N. Pandeya1, Alka Pandey2, R.L. Gupta2 and Kishu Tripathi1
1Saroj Institute of Technology and Management, Lucknow, India.
2Department of Chemistry, Banaras Hindu University, Varanasi, India.
J Pure Appl Microbiol. 2007;1(2):345-349
© The Author(s). 2007
Received: 18/05/2007 | Accepted: 04/10/2007 | Published: 30/10/2007
Abstract

Isatin-3-(isonicotinoyl) hydrazone and substituted isatin-3(isonicotinoyl) hydrazone were synthesized and their antibacterial activity was screened. It was observed that the Mannich base with methtyl, isopropyl and isobutyl group substituted Istain –3 -(isonicotinoyl) hydrazone exhibited higher activity and inhibit the growth of almost all the tested bacteria. Among the series, the least active was the compound residues and the methyl derivative
(II-20) is the most active.

Keywords

Istain-3-(isonicotinoyl) hydrazone, antibacterial activity

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