ISSN: 0973-7510

E-ISSN: 2581-690X

S.N. Pandeya1, Alka Pandey2, R.L. Gupta2 and Kishu Tripathi1
1Saroj Institute of Technology and Management, Lucknow, India.
2Department of Chemistry, Banaras Hindu University, Varanasi, India.
J Pure Appl Microbiol. 2007;1(2):345-349
© The Author(s). 2007
Received: 18/05/2007 | Accepted: 04/10/2007 | Published: 30/10/2007

Isatin-3-(isonicotinoyl) hydrazone and substituted isatin-3(isonicotinoyl) hydrazone were synthesized and their antibacterial activity was screened. It was observed that the Mannich base with methtyl, isopropyl and isobutyl group substituted Istain –3 -(isonicotinoyl) hydrazone exhibited higher activity and inhibit the growth of almost all the tested bacteria. Among the series, the least active was the compound residues and the methyl derivative (II-20) is the most active.


Istain-3-(isonicotinoyl) hydrazone, antibacterial activity

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© The Author(s) 2007. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.