The aim of the present study was to investigate the antimicrobial activity of different organic extracts prepared from biomass and culture supernatant of Lyngbya majuscula against Escherichia coli, Bacillus cereus, Bacillus subtilis, Staphylococcus epidermidis, Enterococcus faecalis and a Yeast Candida albicans. Antimicrobial activity and minimum inhibitory concentration(s) of various extracts were evaluated by disc diffusion assay and broth micro dilution assay, respectively. Results indicated that this cyanobacterium excreted metabolites having broad spectrum antimicrobial activity. Methanolic extract was found to have significant activity against Bacillus subtilis with MIC value 512 µg/ml. HPTLC (high performance thin-layer chromatography) analysis at l 254 nm was performed for the separation of all the chemical constituents from the methanol extract. The antimicrobial activity was compared with standard antibiotic tetracycline and nystatin.
Antimicrobial activity, Cyanobacteria, Lyngbya majuscula, HPTLC, Minimum inhibitory concentration
Share This Article
© The Author(s) 2009. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.