ISSN: 0973-7510

E-ISSN: 2581-690X

M.G. Usha, Upasana Bora and G. Vishwanath
1Department of Microbiology, JJM Medical College, Davangere, India.
J Pure Appl Microbiol. 2015;9(2):1731-1732
© The Author(s). 2015
Received: 01/02/2015 | Accepted: 12/03/2015 | Published: 30/06/2015

Diphtheria is a highly contagious and potentially life threatening bacterial disease caused by Corynebacterium diphtheria1. It is a fatal disease and may cause serious complications if not recognised early and treated promptly.2 Inspite of extensive immunization coverage, there has been many incidents of drop outs in last decade2. Resurgence of diphtheria was reported in some of the countries, mainly due to waning immunity in adults with age, importation of new cases from the endemic regions and probably due to unidentified factors contributing to low incidence of the disease in some regions3. Several factors like inadequate vaccination, poor socio-economic status, ignorance, delayed reporting and nonavailability/delayed administration of diphtheria antitoxin (ADS), possible modifying effect of passively-acquired maternal antibodies in young infants, which could suppress the development of an active immunity following early administration of DPT vaccines-all are contributing to high mortality3.

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