ISSN: 0973-7510
E-ISSN: 2581-690X
Conversion of benzaldehyde to L-Phenylacetyl carbinol (L-PAC) was achieved with growing cells of Hansenula polymorpha in different reactors. Product formation increased (31%) with the subsequent initial reuses of the entrapped cells. Biomass production and PAC formation depleted (40 and 57%, respectively) after 4-5 continuous growth and biotransformation cycles. With the regeneration of the biocatalysts, catalytic activity of the cells was resumed. The highest yields were in a stirred tank reactor (29 g PAC) from 77 g benzaldehyde with 14 repeated uses of entrapped cells.
Benzaldehyde, biotransformation, Hansenula polymorpha
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