Phytochemical Screening and Antimicrobial Activity of EthOH/Water Ziziphus jujuba Seeds Extracts

ISSN: 0973-7510

E-ISSN: 2581-690X

Phytochemical Screening and Antimicrobial Activity of EthOH/Water Ziziphus jujuba Seeds Extracts

Sherif H. Abd-Alrahman¹ , Mounir M. Salem-Bekhit², Manal E.A. Elhalwagy³, Wael M. Abdel-Mageed^4,5 and Awwad A. Radwan^2,6

¹Biochemistry Department, College of Science, King Saud University, PO Box, 2455, Riyadh, 11451, Saudi Arabia.

²Department of Pharmaceutics, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh, Saudi Arabia.

³Biochemistry Department, Faculty of Science for Girls, King Abdulaziz University, P.O Box 51459, Jeddah,-21453, KSA.

⁴Pharmacognosy Department, College of Pharmacy, King Saud University, Riyadh 11451, P. O. Box 2457, Saudi Arabia.

⁵Pharmacognosy Department, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

⁶Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.

J Pure Appl Microbiol. 2013;7(Spl. Edn.: November):813-818

Received: 12/08/2013 | Accepted: 24/10/2013 | Published: 30/11/2013

Abstract

The Ziziphus species (Rhamnaceae family) are considered to be multipurpose plants and have been used as foods, folklore medicines, the environmental protection plants. This study was conducted to isolated and evaluate the antimicrobial activity of ethanol extract of Ziziphus jujuba seeds against sixe bacterial strains by determining minimum inhibitory concentration (MIC) and analyzed their content by using chromatographic techniques to identify the principal bioactive phytochemicals. GC/MS analysis of ethanol extract of Ziziphus jujuba seed revealed the existence of 20component, main components were 13-Heptadecyn-1-ol (12.95%), 7-Ethyl-4-decen-6-one (9.73%), Lineoleoyl chloride (8.54%), Linoleic acid (6.37%), 2,5-Octadecadiynoic acid, methyl ester (5.57%) and Palatinol A (4.81%). The results indicated that the ethanolic extract of Ziziphus jujuba seed contains a many bioactive components that could have advantage offer a platform of using Ziziphus jujuba seed as herbal alternative for the current synthetic antimicrobial agents.

Keywords

Phytochemical Screening, Antibacterial activity, Ziziphus jujuba, Medicinal plants

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