ISSN: 0973-7510

E-ISSN: 2581-690X

G. Balakrishnan , Parimal Roy and T.V. Meenambigai
1Department of Veterinary Microbiology, Madras Veterinary College, Tamil Nadu Veterinary and Animal Sciences University, Chennai – 600 007, India.
J Pure Appl Microbiol. 2015;9(1):831-834
© The Author(s). 2015
Received: 10/11/2014 | Accepted: 09/01/2015 | Published: 31/03/2015
Abstract

Leptospiral serovars namely australis, ballum, hardjo, hebdomadis and pomona were selected as seed bacteria for the preparation of Leptospira vaccines based on the seroprevalence studies conducted using 3605 bovine serum samples of Tamil Nadu, Andhra Pradesh and Gujarat states. By incorporating the above serovars two different kind of adjuvanted pentavalent vaccines were prepared. Vaccine I was adjuvanted with Montanide ISA 206 and vaccine II was adjuvanted with Aluminium hydroxide gel. The two vaccines were found to be safe and potent, hence considered as better vaccines.

Keywords

Bovines, Leptospirosis, Vaccines

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