ISSN: 0973-7510

E-ISSN: 2581-690X

Mohammed A. Ibrahim , Rima Albesharat, Khulud Alsouleman and Linda Ismail
National Commission of Biotechnology, Damascus, Syria.
J Pure Appl Microbiol. 2008;2(1):19-22
© The Author(s). 2008
Received: 01/01/2008 | Accepted: 12/02/2008 | Published: 30/04/2008

The aim of the study was to screen and identify novel activities of Streptomyces isolates from Syrian soil. Streptomyces isolate designated RW6 showed unusual inhibition pattern against Vibrio fluvialis. On the other hand , Streptomyces RW6 showed no antibacterial activities  against  Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Staphylococcus aureus  and Bacillus subtilis.

               Possible involvement of plasmid content of Streptomyces isolate RW6 with its novel antibacterial activity against Vibrio fluvialis was studied. Treatment of the isolate with acridine orange  resulted in curing of the plasmid as demonstrated by agarose gel electrophoresis, and subsequently the loss of novel  pattern of antibacterial activity against Vibrio fluvialis.


Streptomyces, Vibrio fluvialis, plasmids, antibiotic resistance, antibacterial activity

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© The Author(s) 2008. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.