ISSN: 0973-7510

E-ISSN: 2581-690X

Krishna Suresh Babu Naidu1 , Patrick Govender2 and Jamila K. Adam1
1Department of Biomedical and Clinical Technology, Durban University of Technology, Durban 4000, South Africa.
2Department of Biochemistry, University of KwaZulu-Natal, Private Bag X54001, Durban 4000, South Africa.
J Pure Appl Microbiol. 2015;9(Spl. Edn. 2):103-112
© The Author(s). 2015
Received: 20/07/2015 | Accepted: 09/09/2015 | Published: 30/11/2015

Nanotechnology is most promising arena for generating new applications in medicine and advancing rapidly due to the great progress achieved in various fileds including electronics, machanics, cosmetics, food, etc. In order to successfully bifunctionalise nanoparticles for a given biomedical application, a wide range of  chemical, physical and biological factors are to be taken into account. Silver nanoparticles (AgNPs) at nanoscale exhibits strong antibacterial activity vowing to their large surface to volume ratios and crystallographic  surface structure. Nanosilver particles have been widely used in a range of biomedical applications including diagnosis, treatment, medical device coating, drug delivery and personal health care products. With the growing application of nanosilver particles in medical contexts, it is becoming necessary for a better understanding the mechanisms of action, biological interactions and their potential toxicity on exposure. This review aims to provide critical assessment of the current understanding of antibacterial activity, biomedical and clinical applications of silver nanoparticles.


Antibacterial, , Biomedical, Clinical, Nanosilver, Applications

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© The Author(s) 2015. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.