ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Abualgasim Elgaili Abdalla1,2 , Allam Bakheet Kabashi2, Mohamed Elnour Elobaid2, Nooh Mohammed Haj Hamed2, Waddah Abozaid Modawyi2, Ayman Ali Mohammed Alameen1,3 , Khalid Omer Abdalla Abosalif1,2
and Hasan Ejaz1
1Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka – 2014, KSA.
2Department of Medical Microbiology, Faculty of Medical Laboratory Sciences, Omdurman Islamic University, Omdurman, Sudan.
3Department of Chemical pathology, Faculty of Medical Laboratory Sciences, Khartoum University, Khartoum – 11081, Sudan.
J Pure Appl Microbiol, 2019, 13 (3): 1605-1609 | Article Number: 5856 | © The Author(s). 2019
Received: 02/09/2019 | Accepted: 19/09/2019 | Published: 27/09/2019

The present study aimed to investigate the incidence of Methicillin-Resistant Staphylococcus aureus strains (MRSA) and inducible clindamycin resistant S. aureus (ICRSA) among postoperative wound infected patients. A total of 94 S. aureus strains were isolated by conventional laboratory methods from 135 swab samples collected from post-operative wound infected patients in Khartoum State hospitals. The isolated strains were screened for MRSA by using cefoxitin disc. ICRSA strains was detected by D-test and their susceptibility to antimicrobial agents was done by modified Kirby-Bauer’s disc diffusion method. Ninety-four S. aureus isolates were screened for MRSA strains, we found 42 (45%) of isolates were MRSA and 52 (55%) of strains were methicillin-sensitive S. aureus (MSSA) phenotype. The incidence of ICRSA, constitutive clindamycin resistant (CCRSA) and erythromycin resistant (ERSA) strains among S. aureus isolates were 15.9% (15/94), 9% (8/94) and 2.12% (2/94), respectively. ICRSA resistant strains were slightly more frequent among MRSA, when compared with MSSA strains (16.67% (7/42) vs. 15.38% (8/52)). In addition, 33% of ICRSA strains were found resistant to both co-trimoxazole and gentamicin, while, 23% of strains were resistant to vancomycin. This study concluded that MRSA strains was nearly accounted a half of clinical isolates, which need more attention by improving hospitals environment heath quality. ICRSA isolates were detected within both MRSA and MSSA strains and the D test must be implemented as routine susceptibility test to avoided clindamycin treatment failure.


Staphylococcus aureus, wound, MRSA, inducible clindamycin, D-test.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.