Coagulase negative Staphylococcus (ConS) are essentially opportunists  infections that are nearly always associated with abnormal circumstances especially the presence of foreign medical devices such as Intravascular catheters, csf shunts, prosthetic heart valves, prosthetic joints, peritoneal dialysis catheters, haemodialysis shunts, and vascular grafts.  These bacteria are pathogenic especially in immunocompromised patients and malignancies. ConS cause Bacteraemias of various severities. Blood, sputum, urine, wound swabs, pus and transthoracic aspirations were collected.  Standard bacteriological procedures are done to identify and confirm it as ConS. Out of 184 wound swabs 43 were ConS (23.86%), out of 108 blood samples 25 were ConS (23.14%) out of 94 pus sample – 16 were ConS (17.02%).  Out of 33 sputum sample 3 were ConS (9.09%) and out of 14 transthoracic aspirations 1 was Cons (7.14%). Among these S.epidermidis was most commonly isolated 55 out of 102 (53.92%) followed by S. saprophyticus 12 out of 102 (11.76%), S.saccharolyticus 10 (9.80%),
S. intermedius 7 (6.86%), S.capitis 6 (5.88%), S.haemolyticus 5 (4.90%), S.lugdunensis 3 (2.99%), S.hyicus, S.caseolyticus, S.Schleiferi, S. Cohnii 1 each (1%). 32% of the strains were slime positive, 31% produced beta lactamase, 16% were Novobiocin resistant, Methicillin resistance was 29.41%.