ISSN: 0973-7510

E-ISSN: 3207-3212

Rezaie Mehrdad1, Sanaei Dashti Anahita2 , Alamdari Maryam3, Hashemi Zahra1 and NajibKhadijeh Sadat1
1Neonatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
2Professor Alborzi Clinical Microbiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
3Shiraz Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
© The Author(s). 2015
J. Pure Appl. Microbiol., 2015, 9 (4): 3207-3212.
Received: 15/09/2015 | Accepted: 12/11/2015 | Published: 31/12/2015
Abstract

Infections are important causes of morbidity, mortality and prolonged admission among the neonates. It is necessary to treat neonatal infections by empirical antimicrobial drugs, based on the epidemiologic studies of bacterial sensitivity.This study aims to determine the microorganisms involved in neonatal infections and their antibiotic sensitivity patterns. This cross-sectional study enrolled 200 neonates admitted to the central neonatal intensive care unit (NICU) of Shiraz Namazi Hospital from Oct 2013 to March 2014. Samples included blood, urine, CSF, stool, eye discharge, peritoneal fluid, ear secretion and nasal discharge. All the samples underwent culture and antibiotic sensitivity pattern. Statistical analyses were performed using version 16 SPSS software. Totally, 35% of the specimens were positive for microbial agents. The most isolated microorganisms from all samples were Staphylococcusepidermidis(Staph. epidermis) (26.8%) and klebsiella (17.7%). In the nasal and throat samples, Klebsiella was the most isolated microorganism. All Staph.epidermis isolates were sensitive to vancomycin.Staph.epidermis was most resistant to tocloxacilin and erythromycin. Pathogens responsible for neonatal infections and their antibiotic sensitivity patterns may vary over time and with hospitals. So monitoring the microbial epidemiology of neonatal infections and their susceptibility patterns is necessary to choose appropriate antibiotics.

Keywords

Neonatal Intensive Care Unit; Infection; microorganisms; Antimicrobial Resistance.

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© The Author(s) 2015. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.