ISSN: 0973-7510

E-ISSN: 2581-690X

K. Himakar Reddy1, K. Bala Nagi Reddy1, P.V.G.K. Sharma2 and O.V.S. Reddy1
1Department of Biochemistry, Sri Venkateswara University, Tirupati – 517 502, India.
2Department of Biotechnology, Sri Venkateswara Institute of Medical Sciences, Tirupati, India.
J Pure Appl Microbiol. 2009;3(2):769-776
© The Author(s). 2009
Received: 10/07/2009 | Accepted: 16/08/2009| Published: 31/10/2009

Hexane extract (oil) of Dillenia indica seed powder was evaluated for antimicrobial and antioxidant activities. It exhibited broad spectrum of antimicrobial activity. The MIC values for different bacterial and fungal strains varied from 1.0 to 2.0 mg/ml concentration and DIZ from 12 to 28 mm of the extract. Screening for secondary metabolites of the extract revealed the presence of phenols, triterpenoids, carbohydrates and fatty acids. To evaluate antioxidant activity, TLC-DPPH, DPPH, H2O2, ABTS radical, SOD and reducing power activities method were carried out. The distinct antimicrobial activity was observed against prominent pathogens indicates that this oil may be useful in treatment of microbial infections. The hexane extract of D. indica shows moderate antioxidant activity when compared with controls.


Antimicrobial, Antioxidant, Dillenia indica, Secondary metabolites

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© The Author(s) 2009. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.