ISSN: 0973-7510
E-ISSN: 2581-690X
The present study was aimed to investigate the efficacy of honey and citric acid against multidrug resistant clinical isolates of Pseudomonas aeruginosa from infected wounds. A total of twenty-four isolates of Pseudomonas aeruginosa were studied for sensitivity to honey and citric acid on the principle of minimum inhibitory concentration (MIC).The antibiogram suggests that all Pseudomonas aeruginosa isolates were resistant to Gentamicin and susceptible to Ciprofloxacin. The order of antibiotic resistance in Pseudomonas aeruginosa noted was Polymyxin-B > Ceftizoxime > Piperacillin > Tobramycin > Carbenicillin > Ceftazidime > Norfloxacin > Cefepime .The majority (80%) of multidrug resistant Pseudomonas aeruginosa isolates were inhibited by 30 % v/v and 500 micrograms/milliliter of Honey and Citric acid concentration respectively.The present study showed that Pseudomonas aeruginosa isolates resistant to routinely used antibiotics were sensitive to antibacterial action of honey and citric acid. The findings of the present study demonstrated the role of honey and citric acid as antipseudomonal agents.This suggests that antibacterial honey and citric acid have potential to be an effective alternative antibacterial agent.
Pseudomonas aeruginosa, Wound infection, Honey, Citric acid
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