Bacterial cellulose which is produced by several bacteria has played an important role in industry and medicine area based on its unique structural, functional, physical and chemical properties. However, both the scale and cost of production impede a wide range of applications of bacteria cellulose. The paper concludes the current state of knowledge of high-producing strains and discusses the mechanism of cellulose biosynthesis. Cellulose synthase, as the key enzyme, is identified from the structure, the organization of gene and the regulation. The cyclic diguanylic acid regulatory system is important in the progress of bacterial cellulose biosynthesis.
Bacterial Cellulose, Metabolic Network, High-producing Strains, Cellulose Synthase, Regulation
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