Sequence of the isolate was submitted in gene bank and provided with accession number KF996507 and named as Streptomyces antibioticus strain ess_amA8. The GC-MS analysis revealed that presence of 2-methyl propanamide, n-hydroxymethylacetamide, hexanamide, 1,2 enzenedicarboxylic acid, hexadecyl-oxirane, 4-hydroxytetradec-2-ynal, 8-pentadecanone, phenylpropanedioic acid, phenylethyl alcohol and 3-methyl-but anamide. Ethyl acetate Extract of Streptomyces antibioticus was most effective against Streptococcus pyogenes ATCC 19615, Staphylococcus aureus ATCC 25923, Klebsiella pneumonia ATCC 70060, Salmonella typhi ATCC 6539 and Pseudomonas aeruginosa ATTC 27853 respectively.The findings obtained from this study may contribute to development of potentially effective and environmentally safer alternative antibacterials.
Streptomyces antibioticus,GC-MS, Ethyl acetate, hexadecyl-oxirane
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