ISSN: 0973-7510

E-ISSN: 2581-690X

Case Report | Open Access
Dwi Murtiastutik1 , Cita Rosita Sigit Prakoeswa1 and Indah Setiawati Tantular2
1Department of Dermatology Venereology, Faculty of Medicine, Universitas Airlangga – Dr. Soetomo General Academic Hospital, Surabaya 60286, Indonesia.
2Department of Parasitology, Faculty of Medicine, Universitas Airlangga, Surabaya 60132, Indonesia.
J. Pure Appl. Microbiol., 2020, 14 (1): 31-36 | Article Number: 6007 | © The Author(s). 2020
Received: 30/12/2019 | Accepted: 30/01/2020 | Published: 06/02/2020

The majority of HIV / AIDS patients have common secondary infections including of oral candidiasis. Fluconazole can be used to treat oral resistance in candidiasis. Management that can reduce risk can be minimized. However, some evidences suggest that the use of fluconazole is not effective for oral candidiasis. A 34-year-old male patient went to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, with main complaint of discomfort and pain in the tongue. The physical examination showed a white pseudomembrane on the tongue and palate, which could be removed but left reddish and painful marks. The examination from tongue and palate swab found a colony of white Candida albicans and showed resistant to fluconazole, intermediate to ketoconazole, and sensitive to nystatin. The patient received nystatin oral suspension for three times a day as much as 5 ml (500,000 units). The pseudomembrane disappeared on day 10. The medication continued for fourteen days. No sign of recurrent found in two weeks after the treatment. The administration of nystatin can be used as an effective medication for oral candidiasis.


Oral candidiasis, HIV/AIDS patient, fluconazole.

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