Adverse effects of popular antibiotics and multidrug resistant strains of pathogens have lead rapid search for new antimicrobials. Traditional medicine is an important source of potentially useful new drugs. They could be the unique templates that could serve as a starting point for synthetic analogues. The medicinal properties of Tridax procumbens such as wound healing, immunomodulatory properties are well documented. However it is necessary to determine the role of this plant as an antimicrobial agent that also may be helpful in fast wound healing by controlling the pathogens. Successive solvent extraction procedure was utilized to obtain various extracts flowers and leaves of T. procumbens. These extracts were used to study their capacity to control bacterial agents causing urinary tract infections. Agar diffusion method was used in the study. Among the five compounds obtained in the extraction process, quarternary alkaloids were found to be effective, while polar compounds extracts showed poor activity at tested conditions. The determination of MIC and TA dictates the effectiveness of the extracts. Results of the present study indicate that T. procumbens and can be exploited for future antibacterial drugs.
Tridax procumbens, MIC, TA, antibacterial drug
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