ISSN: 0973-7510
E-ISSN: 2581-690X
In our study, the M, M1 and M2 gene of H3N8 equine influenza virus (EIV) were phylogenetic analyzed. Also, the aa sequences of the M1 and M2 proteins were aligned and mapped. The result showed that the M, M1 and M2 gene of all the recent EIV strains of Florida-2 clade isolated after 2007 was under divergent evolution. It evolved into a different clade named Aisan clade, which was distinguished from EIV strains of Florida-2 clade isolated before 2007 and was more genetic similar to the European clade. This was also revealed by aa sequence analysis of M1 and M2 protein. In addition, the phylogenetic tree of M2 gene indicated that it evolved in different pattern from the complete M and M1 gene. The M1 and M2 gene of two horse-derived influenza viruses of A/Swine/Chibi/01/2005 and A/Swine/Anhui/01/2006 was confirmed under frozen evolution here. Our studies enrich our knowledge of the M, M1 and M2 gene of H3N8 EIV and will make foundation of further research on it.
Matrix Gene, Equine Influenza Virus, Evolution, Phylogenetic Analysis
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