ISSN: 0973-7510

E-ISSN: 2581-690X

Meher Rizvi1 , Abida Malik1, Fatima Khan1, M. Azam1, Anjum Parvez2, Haris M. Khan2 and Indu Shukla1
1Department of Microbiology, JN Medical College and Hospital, AMU, Aligarh, India.
2Department of Medicine, JN Medical College and Hospital, AMU, Aligarh, India.
J Pure Appl Microbiol. 2012;6(Spl. Edn.: October):63-66
© The Author(s). 2012
Received: 04/03/2012 | Accepted: 10/06/2012 | Published: 31/10/2012
Abstract

Chikungunya is an emerging disease in North India. The disease typically presents as an acute illness with symptoms of fever, skin rash and incapacitating arthralgia. The modern lifestyles may amplify an epidemic through travel, population ageing, and production of solid waste that can shelter Aedes mosquito. Consecutive febrile patients were screened for malaria and dengue by peripheral blood smear and rapid immunochromatographic assay (detecting IgM and IgG) respectively. Patients negative for malaria and dengue were screened for acute chikungunya infection by IgM ELISA (SD Bioline, India). A total of 1400 patients presented with fever. Of these malaria was diagnosed in 253(18.1%) patients and 262(18.7%) were found to have dengue. A total of 67 people presenting with unexplained fever were investigated for chikungunya infection, out of which 12 cases (17.9%) were found to be positive for chikungunya antibody. Prevalence was higher in females (p<0. 006), and also highest for the age group of 11 to 30 years. Amongst the patients found positive for chikungunia fever with chills 16.6% and thrombocytopenia 25% were the main presentation. However, none of these patients complained of rashes, arthralgia or myalgia. A significant prevalence of chikungunya 17.9 % was observed in Aligarh in 2010. The presentations most strongly associated with chikungunya apart from high grade fever were thrombocytopenia and chills. This highlights the all the patients with fever and chills along with bleeding tendencies should be screened for chikungunia as well.

Keywords

Chikungunya, Tertiary Care Centre, Aligarh

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