Antimicrobial activity of a supramolecular system resulting from hydrogen bonding interaction of mesoporphyrin(ix )dihydrochloride (3) with 5, 10, 15, 20 – meso tetrakis pentafluorophenyl 21H, 23H porphine (4) was investigated using the Agar diffusion and Poison plate methods. Compound (5) was shown to display enhanced antimicrobial activities against S. aureus, C. albicans and E. coli in comparison to that of either (3) or (4), synthetic ampicillin and nystatin.
Enhanced Antimicrobial activity, hydrogen bonding, supramolecular Chemistry, Agar well diffusion, Poison plate method
© The Author(s) 2011. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.