A field experiment was carried out during the winter (rabi)  seasons of 2010-2011 and 2011-2012 at Banaras Hindu University, Varanasi, to study the effect of nutrient management practices on the productivity and profitability of Indian mustard [Brassica juncea (L.) Czernj. & Cosson] under irrigated condition. The experiment was laid out in randomized block design comprised eight treatment combinations in three replications. The study revealed that conjunctive use of Azotobacter + PSB seed treatment + 100% (N + P2O5) recorded maximum growth parameters viz. plant height, number of functional leaves, dry matter accumulation and number of branches, yield attributes viz. number of siliquae, length of siliqua, seeds/siliqua and 1000-seed weight and seed as well as stover yields remained at par with 50% (N + P2O5), Azotobacter + PSB seed treatment 75% (RDNP).  The maximum gross return (‘ 29,680 and 43,282) and net return (‘ 15,717 and 25,600) were obtained with Azotobacter + PSB + 100% RDNP, however maximum output: input ratio (1.16 and 1.50) was recorded under Azotobacter + PSB + 75% RDNP.