The study showed the effect of Vitex negundo crude extracts on mast cells degranulation activity. It was noticed that 100mg/kg.dose of the herbal drug when given p.o. to the albino rats showed 72% mast cells stabilizing activity which was similar to the standard drug Prednisolone .Only 20% cells were found disrupted the detail phytochemistry of extract showing this activity is under the process.
Vitex negundo, Mast cells, degranulation , Anti-inflamatory
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