ISSN: 0973-7510

E-ISSN: 2581-690X

E. Venumadhav1, P. Sai Praveen2, T. Neha2, P.Bhargavi2, G.Sudhakara Sai Babu2 and G. Devala Rao2
1Chief Operating Officer, Veeda CR, Ahmedabad, Gujarat, India.
2KVSR Siddhartha College of Pharmaceutical Sciences, Vijayawada – 520 010, India.
J Pure Appl Microbiol. 2011;5(1):485-487
© The Author(s). 2011
Received: 21/06/2010 | Accepted: 04/08/2010 | Published: 30/04/2011
Abstract

Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Ethacridine Lactate in pure samples and pharmaceutical formulations are described in the present study. They are based on the formation of colored species by treating with P-Dimethylaminocinnamaldehyde ( PDAC) reagent (Method A, lmax 600 nm) or Methyl orange (MO) reagent (Method B, lmax 420 nm) or Bathophenanthroline (BPL) reagent in presence of Ferric chloride (Method C, lmax 600 nm). These methods were extended to the analysis of pharmaceutical preparations and results are compared with the reference method (USP).

Keywords

Spectrophotometry, Ethacridine, Pharmaceutical preparations

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