Three simple and sensitive visible spectrophotometric methods (A-C) for the determination of Ethacridine Lactate in pure samples and pharmaceutical formulations are described in the present study. They are based on the formation of colored species by treating with P-Dimethylaminocinnamaldehyde ( PDAC) reagent (Method A, lmax 600 nm) or Methyl orange (MO) reagent (Method B, lmax 420 nm) or Bathophenanthroline (BPL) reagent in presence of Ferric chloride (Method C, lmax 600 nm). These methods were extended to the analysis of pharmaceutical preparations and results are compared with the reference method (USP).
Spectrophotometry, Ethacridine, Pharmaceutical preparations
© The Author(s) 2011. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.