ISSN: 0973-7510

E-ISSN: 2581-690X

Open Access
Zena K. Khalil, Alyaa M. Hadi and Saif S. Al-Kamil
Middle Technical University, Technical medical institute, Al-Mansur, Iraq.
J Pure Appl Microbiol. 2018;12(3):1455-1463
https://doi.org/10.22207/JPAM.12.3.49 | © The Author(s). 2018
Received: 10/06/2018 | Accepted: 20/07/2018 | Published: 30/09/2018
Abstract

The study included 234 patients attended to Iben AL-Haithem hospital of ophthalmology in Baghdad city having microbial keratitis , at age of (18-81) years for the period from  September 2017- April 2018 . there were  147 ( 63% ) patients with bacterial keratitis and 87 (37%) with fungal keratitis . Men with bacterial keratitis represented 60% (88) and women 40% (59) , while men with fungal keratitis were 61% (53) and women 39% (34),  the number of the patients with bacterial keratitis were 82(56%) and 51(59%) with fungal keratitis from Baghdad while the internally displaced were 62(44%) with bacterial and 36(41%) with fungal keratitis , the percentage of patients with bacterial keratitis and fungal keratitis were both (34%)  at mean age of 73 ± 2.3 y . Most patients with bacterial keratitis recorded having diabetes mellitus(39%) while the diabetic with fungal keratitis represented (41%) , The results revealed that gram-positive bacteria was 102 (69%) and gram negative 45 ( 31%) , S.aureus was the most common cause of bacterial keratitis42(29%),  followed by S.epidermidis  36(24%) then Streptococcus spp. 24(16%), Pseudomonas spp. 17 (12%) , Proteus,  spp. 13 (9%), Escherichia coli  9(6%) and Enterobacter spp 6(4%)  while Aspergillus fumigates represented 26(30%) as the most common cause of fungal keratitis , Aspergillus flavus 19(22%), Aspergillus niger 16(18%)  , Pencillium spp 11(13%), Fusarium oxysporium. 8(9%) , Fusarium solani 5(6%) and Candida spp 2(2%) . S. aureus isolates were susceptible to Cloramphenicol and  Ciprofloxacin (83%)  while they were resistant to Clindamycin (57%) . S.epidermidis isolates were susceptible to   Cloramphenicol and Amikacin (86%) ,Streptococcus spp were susceptible to  Tetracycline and Clindamycin  (88% ,83%) , Pseudomonas spp showed their high susceptibility to Tetracycline(96%) followed by Cloramphenicol and Ciprofloxacin (88%) both each, Enterobacter spp were susceptible to  Tetracycline and Gentamicin (100%) while  E.coli  were susceptible to  Cloramphenicol (100%)  followed by Ciprofloxacin and  Gentamicin (89%) both, fungal isolates were susceptible to all types of antibiotics used in the study as  (98%) of Aspergillus spp isolates were sensitive to Itraconazole (98%) Voriconazole, Amphotericin B and Natamycin (95%,93% ,92%) respectively, Pencillium spp. were sensitive to Amphotericin B (100%) then Natamycin and Itraconazole (91%) both, Fusarium spp were sensitive to Natamycin and Itraconazole (100%), Candida isolates were sensitive (100%) to Amphotericin B, Natamycin and Voriconazole.

Keywords

Bacterial and fungal keratitis, Antibiotic susceptibility, Ibn Al-Haitham hospital of ophthalmology Baghdad, Iraq

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© The Author(s) 2018. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.