The present research is to compare the growth parameters of six pathogenic and non pathogenic Vibrio parahaemolyticus (V. parahaemolyticus) strains on shrimp at 37 °C. The V. parahaemolyticus counts on inoculated cooked shrimp (Litopenaeus vannamei) was enumerated. The growth parameters of pathogenic V. parahaemolyticus (pVp) and nonpathogenic V. parahaemolyticus (npVp) were obtained by fitting growth data to the modified Gompertz model. The specific maximum growth rate (µ_max) of tdh gene positive (tdh⁺) pVp Vp2 (tdh⁺/trh^–), Vp6 (tdh⁺/trh^–), Vp16 (tdh⁺/trh^–) was 2.17, 2.32 abd 1.7 (log₁₀ CFU/g)·h^-1 respectively. The µ_max of trh gene positive (trh⁺) pVp Vp3 (tdh^–/trh⁺) and Vp 19 (tdh^–/trh⁺ ) was 1.24 and 1.8 (log₁₀ CFU/g)·h^-1 respectively, The µ_max of npVp Vp18 (tdh^–/trh^–) was 1.95 (log₁₀ CFU/g)·h^-1. The lag time (ë) of tdh⁺ pVp Vp2, Vp6 and Vp16 was 0.55, 1.04 and 0.83 h respectively. The ë of trh⁺ pVp Vp3 and Vp19 was 0.13 and 0.39 h respectively, the lag time (ë) of npVp Vp18 was 0.32 h. The maximum population density (N_max) of tdh⁺ pVp Vp2, Vp6 and Vp16 was 9.03, 9.43 and 9.12 log₁₀ CFU/g respectively. The N_max of trh⁺ pVp Vp3 and Vp19 was 9.19 and 9.22 log₁₀ CFU/g respectively, The µ_max of npVp Vp18 was 9.42 log₁₀ CFU/g. It is revealed that the clinical tdh⁺ pVp grow faster than the npVp , trh⁺ pVp and food isolated tdh⁺ pVp. The study could contribute to the strain selection in predictive model construction and provide important information for government to set effective management measures to ensure food safety.