ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Muazzam Sheriff Maqbul1, Ali Mohamed Alshabi2, Aejaz A. Khan3, S.M. Shakeel Iqubal3 , Tasneem Mohammed3, Ibrahim Ahmed Shaikh4, Areej Dawoud3, Uday M. Muddapur5, Mohammed Shahid Hussain6 and S.K. Singh7
1Faculty of Microbiology and Immunology, Ibn Sina National College of Medical Sciences, Al Mahjar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia.
2Department of Clinical Pharmacy, College of Pharmacy, Najran University, Najran, Saudi Arabia.
3Department of General Science, Ibn Sina National College of Medical Sciences, Al Mahajar Street: 31906, Jeddah 21418, Kingdom of Saudi Arabia.
4Department of Pharmacology, College of Pharmacy, Najran University, Najran, Saudi Arabia.
5Department of Biotechnology, KLE Technological University, BVB Campus, Hubballi, 580031, India.
6Department of Orthodontics and Dentofacial Orthopedics, M. A. Rangoonwala Dental College, Pune, Maharashtra, India.
7Department of Chemistry, GGV (Central University), Bilaspur (C.G) – 495009, India.
J. Pure Appl. Microbiol., 2020, 14 (1): 255-260 | Article Number: 5994
https://doi.org/10.22207/JPAM.14.1.26 | © The Author(s). 2020
Received: 13/12/2019 | Accepted: 18/03/2020 | Published: 28/03/2020
Abstract

The present study aimed to determine the susceptibility of Pseudomonas aeruginosa strains isolated from patients with nosocomial infections to standard synthetic chemical antibiotics and organic ethanoic acids derived from local produce. The minimum inhibitory concentrations (MIC) of the  standard synthetic antibiotics determined from standard e-test results and antibiotic sensitivity tests showed many multidrug-resistant strains among the isolates. We compared the susceptibility of  these strains  to organic ethanoic acids derived from different sources using standard microbiological assays. All strains of P. aeruginosa isolated from the patients were susceptible to the organic ethanoic acids with a satisfactory MIC and minimum bactericidal concentrations. Therefore, organic ethanoic acids were more effective against P. aeruginosa than standard synthetic antibiotics.

Keywords

Antimicrobial activity, Pseudomonas aeroginosa, ethanoic acid, Nosocomial infection, Immuno suppressed, Vinegar.

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