Coronary artery diseases are considered to be the most common of cardiac illnesses as well as the most important factor contributing to acute myocardial infarction, which in turn is the most prevalent cause of death and disability in many countries. Although Epidemiologic studies have confirmed the role of many risk factors, such as hypercholesterolemia, diabetes, hypertension, smoking, obesity and increased blood glucose, there remains a variety of other parameters, such as vitamin D deficiency, which also increase the occurrence of coronary arterial diseases. This study aims to evaluate the level of vitamin D3 serum levels in patients suffering from acute myocardial infarction and comparing the finds to that of healthy individuals with no previous history of cardiac diseases. This case-control study was performed on patients suffering from acute myocardial infarction admitted to the Ekbatan hospital of Hamadan, Iran. Checklists were designed to gather data form 24 clauses of the subjects’ medical files. Gathered data were processed and studied analytically. This research enrolled 40 patients with acute myocardial infarction as well as 40 healthy patients with no known history of cardiac diseases. Serum Vitamin D3 levels were lower in patients suffering from myocardial infarction than that of the control group (20.60 to 22.05), however this difference lacks statistical significance (P=0.284). Subjects with adequate serum levels of vitamin D3 had a 70% lesser chance of experiencing a myocardial infarction (chance ratio 0.30), however according to the Wald test, this relevance has no statistical significance (P=0.187). Higher levels of serum Vitamin D3 decreases the chance of acute myocardial infarction, although confirming this find as a clinical evidence requires repetition on larger groups.
Acute myocardial infarction, Vitamin D3 serum levels, Hamedan.
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