ISSN: 0973-7510

E-ISSN: 2581-690X

Sherif H. Abd-Alrahman1 , Mounir M. Salem-Bekhit2 and Manal E.A. Elhalwagy3
1Department of Biochemistry, College of Science, King Saud University, PO Box, 2455, Riyadh, 11451, Saudi Arabia.
2Department of Pharmaceutics, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh, Saudi Arabia.
3Biochemistry Department, Faculty of Science for Girl’s, King Abdulaziz University, P.O Box 51459, Jeddah,-21453, Saudi Arabia.
J Pure Appl Microbiol. 2013;7(Spl. Edn.: November):379-385
© The Author(s). 2013
Received: 29/08/2013 | Accepted: 02/11/2013 | Published: 30/11/2013
Abstract

The aims of this study were to test the antibacterial activity and chemical composition of Ziziphus jujuba extract. The extract was obtained using 50% aqueous – ethanol extraction solution to extract Ziziphus jujuba seeds. The extract was prepared and evaluated for antimicrobial activity against six bacterial strains by determining minimum inhibitory concentration (MIC). The results revealed that the 50% aqueous – ethanol extract is potent in inhibiting bacterial growth of both gram-positive and gram negative bacteria. The chemical composition of fenugreek was analyzed by gas chromatography/mass spectroscopy (GC/MS). The 13-Heptadecyn-1-ol (12.95%), 7-Ethyl-4-decen-6-one (9.73%), Lineoleoyl chloride (8.54%), Linoleic acid (6.37%), 2,5-Octadecadiynoic acid, methyl ester (5.57%) and Palatinol A (4.81%) were the highest abundant compounds out of total 20 compounds were identified in the Ziziphus jujuba seeds extract.

Keywords

Ziziphus jujuba, Chemical Composition, GC-MS, Antibacterial activity

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