Present study was undertaken to study changing trend of antimicrobial sensitivity of enteric fever causing Salmonella. A total of 2431 strains of Salmonella Typhi and Salmonella Paratyphi A isolated from blood during the period 2008-2010 were included in the study. Ninety percent of Typhi and ninety six percent Paratyphi A isolates were sensitive to Chloramphenicol while sensitivity to ceftriaxone and fluoroquinolones was 89% and 87% respectively. With this emerging trend of increasing sensitivity of enteric fever causing Salmonella to Chloramphenicol, it requires scientific consensus as to whether Chloramphenicol can be kept as reserve drug for cases of quinolone and third generation cephalosporin treatment failure and complicated cases of enteric fever.
Salmonella, antibiogram, Chloramphenicol
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