ISSN: 0973-7510
E-ISSN: 2581-690X
Bacteria are posing a huge threat to human race by becoming resistant to antibiotics. Tetracyclines are broad spectrum antibiotics extensively used for treating variety of human and animal diseases and as growth promoter in animal husbandry.Escherichia coliis not the primary target of tetracycline but their overuse has created an overwhelming level of resistance in E. coli. In this experiment clinical isolates of E. coli (n=157) were collected from a tertiary care hospital in Pakistan and were checked for their resistance patternto tetracycline by modified Kirby-Bauer disc diffusion methods. Significant resistance (93%) was observed among the tested isolates. This substantial resistance indicates the widespread misuse of tetracycline, putting strong selection pressure on Escherichia coli to evolve resistance.
Antibiotics, Tetracycline, Escherichia coli, MDR
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