ISSN: 0973-7510

E-ISSN: 2581-690X

Shehab M. Abd El-Kader1 Mohammed H. Saiem-Aldahr2 and Osama H. Al-Jiffri2
1Department of Physical Therapy, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
2Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
J. Pure Appl. Microbiol., 2016, 10 (2): 879-885
© The Author(s). 2016
Received: 28/03/2015 | Accepted: 24/06/2015 | Published: 30/06/2016
Abstract

Chronic hepatitis C virus infection is usually associated with abnormal liver enzymes, lipid profile and glucose hemostasis. The beneficial effects of aerobic exercise have been a matter of controversy in the field of CHC virus infection management. Objective: The aim of this study was to measure the impact of aerobic exercise training on glucose hemostasis, liver enzymes and lipid profile abnormalities among patients with CHC virus infection. Sixty non-cirrhotic CHC virus infection patients with abnormal lipid profile & non diabetic with insulin resistance. Patients were divided in to two equal groups. The first group received aerobic exercise training, three sessions per week for three months in addition to their antiviral treatment. The second group (B) received only their antiviral treatment. The mean values of alkaline phosphatase (ALP), alanine aminotransferase  (ALT), aspartate aminotransferase (AST), gamma– glutamyltransferase (GGT), insulin, homeostasis model assessment-insulin resistance- index (HOMA-IR), total cholesterol (TC), low density lipoprotein cholesterol (LDL-c) and triglycerides (TG) were significantly decreased in group (A), where the mean value of the quantitative insulin-sensitivity check index (QUICKI) and high density lipoprotein cholesterol (HDL-c) were significantly increased, while there were no significant changes in group (B) Also; there was a significant difference between both groups at the end of the study. Treadmill walking exercise training modulates glucose hemostasis, liver enzymes and lipid profile abnormalities among patients with CHC virus infection.

Keywords

Liver Enzymes; Glucose Hemostasis; Blood Lipids; Chronic Hepatitis C; Aerobic Exercise.

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© The Author(s) 2016. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.