The antimicrobial potential of various fractions of two Solanum species were evaluated against five bacteria and four pathogenic fungi, using microbroth dilution assay. These plants are widely used in Ayurveda and traditional system of medicines in India to treat various kinds of microbial infections and other disorders. The extracts of Solanum xanthocarpum and Solanum trilobatum exhibited antimiciobial activity in a range of 1.12 to 5.0 mg/ml against Salmonella typhi, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus cereus. Hexane extracts of B. lacera and Solanum trilobatumare found to be active against the Candida albicans, Aspergillus fumigatus, A. niger and A. flavus in a range of 1.12 to 20.0 mg/ml. The studies were repeated in triplicates at two laboratories to confirm the results.
Antifungal, Antimicrobial, Plant extracts, Susceptibility testing
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