ISSN: 0973-7510

E-ISSN: 2581-690X

Research Article | Open Access
Aakriti1, Dildeep Bali1, Preeti Sharma2* , Vijaya Dhar Bhatt1, Prashant Bhasin1,  Era Arora1, Suhrab Singh1 and Pradeep Kumar2
1Department of Conservative Dentistry and Endodontics, Santosh Medical and Dental College, Ghaziabad – 201009, India.
2Department of Biochemistry, Santosh Medical and Dental College, Ghaziabad – 201009, India.
J Pure Appl Microbiol, 2019, 13 (3): 1725-1735 | Article Number: 5771 | © The Author(s). 2019
Received: 30/06/2019 | Accepted: 08/08/2019 | Published: 29/09/2019

The complete microfloral debriment of the root canal is possible only through successful endodontic treatment. Due to complexicity constraints of root canal system complete microfloral removal by simply mechanical instruments is not sufficient. Therefore we aim to evaluate the antimicrobial efficacy of five different intracanal medicaments such as calcium hydroxide, chlorhexidiene, octenidol, endosepton and calcium hydroxide and chlorhexidine against Enterococcus faecalis.The Antibacterial activity of aforesaid medicaments was done against Enterococcus feacalis using agar disk diffusion method, over a period of 24 hrs and 72 hrs. The samples were divided into 6 groups. The zone of inhibition was measured after 24 and 72 hrs and were recorded in millimeters and compared with respect to control. There was a significant difference in the mean zone of inhibition at 24 and 72 hrs between calcium hydroxide, endoseptone, octenidol, calcium hydroxide and chlorohexidine combination, chlorohexidine and control group. Chlorohexidine was found to have maximum inhibitory efficacy followed by calcium hydroxide and chlorohexidine combination. Within the limitations of this study it may be concluded that Chlorhexidine can be used as an efficient intracanal medicament.


Intracanal medicament, Octenidol, Endoseptone, Chlorhexidine.

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© The Author(s) 2019. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.