ISSN: 0973-7510

E-ISSN: 2581-690X

K. Vithiya, Rajendran Kumar and Shampa Sen
1Industrial Biotechnology Division, School of Bio Sciences and Technology, VIT University,Vellore- 632014, Tamil Nadu, India.
J Pure Appl Microbiol. 2014;8(4):3263-3268
© The Author(s). 2014
Received: 18/02/2014 | Accepted: 21/04/2014 | Published: 31/08/2014

Increasing resistance of microorganisms to antimicrobial agents has increased the rates of mortality and morbidity from treatment failures indicating a serious threat in near future. Bacillus thuringiensis SSV1 was isolated from soil and growth media was optimized with efficient carbon, nitrogen and metal sources. Stable spherical shaped silver oxide nanoparticles of 10-40 nm diameters were synthesized extracellularly using bacterial culture supernatant. The antimicrobial activity of silver oxide nanoparticles of various concentrations was investigated against pathogenic bacteria. The results showed that silver oxide nanoparticles are as effective as silver nanoparticles against bacteria.


Optimization, Bacillus thuringiensis, silver oxide nanoparticles, antimicrobial activity

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© The Author(s) 2014. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.