Increasing resistance of microorganisms to antimicrobial agents has increased the rates of mortality and morbidity from treatment failures indicating a serious threat in near future. Bacillus thuringiensis SSV1 was isolated from soil and growth media was optimized with efficient carbon, nitrogen and metal sources. Stable spherical shaped silver oxide nanoparticles of 10-40 nm diameters were synthesized extracellularly using bacterial culture supernatant. The antimicrobial activity of silver oxide nanoparticles of various concentrations was investigated against pathogenic bacteria. The results showed that silver oxide nanoparticles are as effective as silver nanoparticles against bacteria.
Optimization, Bacillus thuringiensis, silver oxide nanoparticles, antimicrobial activity
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