Antimicrobial resistance analysis by 16 different antibiotics was done on 24 isolates of Salmonella enterica belonging to six different serotypes viz S. Virchow (1), S. Heidelberg (5), S. Kentucky (1), S. Agona (1), S. Haifa (14) and two rough strains. The results revealed that the Salmonella isolates were sensitive to ciprofloxacin, chloramphenicol and norfloxacin, nalidixic acid and co-trimoxazole, co-trimazine, gentamicin, amikacin and streptomycin and cephalexin in the decreasing order of frequency. All the strains were found resistant to ampicillin and 75% isolates were resistant to nitrofurantoin and colistin. Twenty isolates exhibited multiple drug resistance against 3 to 9 antibiotics with Multiple Antibiotic index ranging from 0.06 to 0.56. MAR index of 0.37 was found in maximum number of isolates (8) which were resistant to six different antimicrobials. The dendrogram based on resistotyping pattern differentiated 24 isolates into 19 resistance patterns (resistotypes) indicating the validity of this test for differentiating the strains to a level of 97.8%. All 24 Salmonella isolates revealed 65.9% average genetic similarity and level of similarity ranged between 20% to 100%.