In the present study we have carried out to evaluate the antibacterial activity of crude extracts from the whole plant of Swertia chirata Buch.-Hams. Hexane, ethyl acetate and methanol extracts were obtained by cold percolation method and their activity was carried out with gram positive and gram negative bacterial strains. Preliminary phytochemical screening was performed for all the extracts. In the present results ethyl acetate extract inhibited many bacteria with MIC values ranging from 0.312 to > 1 mg/ml. Phytochemical screening revealed the presence of terpenoids, steroids, flavonoids, alkaloids and carbohydrates. This study showed that S. chirata can be one of the potential sources of new antibacterial agents for the tested bacterial strains.
Secondary metabolites, antibacterial activity
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