ISSN: 0973-7510

E-ISSN: 2581-690X

K. Balaraju1 , S. Arokiyaraj1, P. Agastian1, N. Thomas Paulraj1 and S. Ignacimuthu2
1Department of Plant Biology and Biotechnology, School of Life Sciences, Loyola College, Chennai-600 034, India.
2Entomology Research Institute, Loyola College, Chennai – 600 034, India.
J Pure Appl Microbiol. 2008;2(1):223-226
© The Author(s). 2008
Received: 20/02/2008 | Accepted: 24/03/2008 | Published: 30/04/2008

In the present study we have carried out to evaluate the antibacterial activity of crude extracts from the whole plant of Swertia chirata Buch.-Hams. Hexane, ethyl acetate and methanol extracts were obtained by cold percolation method and their activity was carried out with gram positive and gram negative bacterial strains. Preliminary phytochemical screening was performed for all the extracts.  In the present results ethyl acetate extract inhibited many bacteria with MIC values ranging from 0.312 to > 1 mg/ml. Phytochemical screening revealed the presence of terpenoids, steroids, flavonoids, alkaloids and carbohydrates. This study showed that S. chirata can be one of the potential sources of new antibacterial agents for the tested bacterial strains.


Secondary metabolites, antibacterial activity

Article Metrics

Article View: 698

Share This Article

© The Author(s) 2008. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.