ISSN: 0973-7510
E-ISSN: 2581-690X
The antibacterial activity of ethanolic and aqueous extracts of Gongronema latifolium and Ocimum gratissimum on E. coli and Salmonella typhi were determined using disc diffusion method. The antibacterial effect of aqueous extracts of Gongronema latifolium was negative on both test organisms and the aqueous extracts of Ocimum gratissimum showed very little zone of inhibition on E. coli (3.00mm) diameter and on Salmonella (2.00mm) diameter. Ethanolic extracts of both Gongronema latifolium and Ocimum gratissimum showed little zone of inhibition on E. coli and Salmonella typhi, which was not greater than 3.00 mm diameter. The minimum inhibitory concentration (MIC) evaluated with both ethanolic and aqueous extracts of Ocimum and Gongronema of various concentrations observed did not show any zone of inhibition. The results suggested that the extracts have low potential for use in the treatment of enteric diseases caused by pathogenic bacteria.
Gongronema latifolium, Ocimum gratissimum, antibacterial activity, Escherichia coli and Salmonella typhi
© The Author(s) 2008. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License which permits unrestricted use, sharing, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.