In the present study the methanol extract of stem bark of Schinus terebinthifolius was evaluated at different concentration (4000, 2000, 1000 and 500 µg/mL) against the growth of some plant and human pathogenic bacteria namely; Bacillus subtilis, Escherichia coli, Ralstonia solanacearum, Erwinia amylovora and Pectobacterium carotovorum subsp. carotovorum using the Kirby-Bauer disc diffusion susceptibility test. The methanol stem bark extract presented a moderate activity against the studies bacterial pathogens B. subtilis, E. coli and R. solanacearum, where other bacterial strains (E. amylovora and P. carotovorum subsp. carotovorum) were showed resistances to the methanol extract.