There is worldwide interest in searching for the safe and effective novel antibacterial compounds of plant origin for the control of human pathogenic bacteria. In this study an attempt was made to determine the in–vitro antibacterial activity of leaves of Adhatoda vesica, Vitex negundo and rhizome of Acorus calamus against human pathogenic bacteria Staphylococcus aureus and Escherichia coli. The preliminary antibacterial activity was performed by agar well diffusion method. All test samples of aqueous extract showed inhibitory effect on both of test pathogens. Maximum activity against pathogen was found to be in A. vesica followed by A. calamus and V. negundo. The results obtained in the present study suggest that A. vesica, A. calamus and V. negundo can be used in treating diseases caused by these test organisms.
Adhatoda vesica, Vitex negundo, Acorus calamus, antibacterial activity
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